Figure 3From: Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell linesEffects of TAK733 on the signaling of the MAPK and PI3K/AKT pathways by Western blot analysis. Melanoma cell were exposed for 24 hours to solvent (DMSO) or various concentrations of TAK733. a) NRASQ61 mutated cutaneous melanoma cell lines; b) GNAQ or GNA11 mutated uveal melanoma cell lines; c) BRAFV600E mutated cutaneous melanoma cell lines.Back to article page