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Table 1 Statistical analysis of immunohistochemistry on treated tumor tissues

From: Interferon-α enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma

 

Control(n = 5 mice)

IL-24(n = 5 mice)

IFN-α(n = 5 mice)

IL-24 and IFN-α(n = 5 mice)

P-value

MMP

74.0 ± 8.5

66.2 ± 10.2

48.0 ± 10.3*

2.0 ± 1.9*†‡

<0.001

OPN

68.0 ± 12.8

0.6 ± 0.9*

9.2 ± 3.7*†

0.6 ± 0.5*‡

<0.001

VEGF

17.8 ± 4.7

1.6 ± 1.1*

1.4 ± 1.5*

0.8 ± 1.1*

<0.001

XIAP

90.8 ± 3.6

0.8 ± 0.4*

79.0 ± 7.0†

0.6 ± 0.5*‡

<0.001

  1. * significant difference compared to the control group,
  2. † significant difference compared to the IL-24 group.
  3. ‡ significant difference compared to the IFN-α group.