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Figure 2 | Molecular Cancer

Figure 2

From: Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection

Figure 2

High expression levels of cyclin B1, Sec62, and Birc3 in the patients with recurrent HCC. A. The mRNA (left) and protein (right) expression of cyclin B1 was significantly higher in the patients with recurrent HCC than in those with non-recurrent HCC and in the healthy controls (p < 0.001). However, no difference was found between the non-recurrence and healthy groups (p > 0.05). B. The mRNA (left) and protein (right) expression of Sec62 were significantly higher in the patients with recurrent HCC than those with non-recurrent HCC and in the healthy controls (p < 0.001). However, no difference was found between the non-recurrence and healthy groups (p > 0.05). C. The mRNA (left) and protein (right) expression levels of Birc3 were significantly higher in the patients with recurrent HCC than in those with non-recurrent HCC and in the healthy controls (p < 0.001). However, no difference was found between the non-recurrence and healthy groups (p > 0.05). * Compared with non-recurrence group. # Compared with the healthy group. The mRNA expression levels were quantified using quantitative PCR. GAPDH was used as the endogenous control for the mRNA levels. The protein levels were examined by western blotting. β-actin was used as the endogenous control for the protein levels.

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Molecular Cancer

ISSN: 1476-4598