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Figure 2 | Molecular Cancer

Figure 2

From: miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer

Figure 2

The genomic structure of the LOC554202 miR-31 is preserved in the BC cell lines used in this study. (A) Schematic representation of the mapping of the LOC554202 exons, the CpG island and miR-31 with respect to BAC clones RP11-344A7 and RP11-354P17. The mapping was confirmed by genomic PCR analysis. The size of the PCR product of each amplicon is shown on the left. ERVK6 was used as a positive control for the total genomic DNA. (B) Genomic PCR analysis of each exon of LOC554202 and miR-31 in the BC cell lines used in this study. The size of the PCR product of each amplicon is shown on the left. ERVK6 was used a positive control for the total genomic DNA.

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