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Figure 5 | Molecular Cancer

Figure 5

From: Antitumor activity of motesanib alone and in combination with cisplatin or docetaxel in multiple human non–small-cell lung cancer xenograft models

Figure 5

Effect of motesanib plus cisplatin treatment on cell proliferation in vitro. Calu-6 cells plated at 3000 cells/well in 96 well plates were treated with motesanib (0, 10, 100, or 1000 nM) plus serial dilutions of cisplatin (0.01 to 10,000 ng/mL) for 72 hours. Cell viability was assessed using the ATPlite™ 1-step luminescence assay (PerkinElmer, Waltham, MA) and is expressed as a percentage of control (ie, 0 ng/mL cisplatin). Identical experiments were performed using A549, NCI-H358, NCI-H1299, and NCI-H1650 cells (not shown).

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Molecular Cancer

ISSN: 1476-4598