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Figure 6 | Molecular Cancer

Figure 6

From: microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer

Figure 6

miR-146a inhibits LPA-induced cytokine expression. 25 μM LPA was used to induce cytokine expression from human gastric carcinoma SNU638 cells. LPA significantly enhanced expression of IL-6, IL-8, IL-23A, CCL5, CSF-1 and PDGFB, which was measured using qPCR and shown relative to the expression level in untreated control cells. This response is reduced in miR-146a-transfected cells. Data are shown as mean ± S.D., n = 4, * = P < 0.05, ns = non significant.

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Molecular Cancer

ISSN: 1476-4598