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Table 3 Comparison in gene expression level between ER positive and negative tumors

From: Expression profiling of ion channel genes predicts clinical outcome in breast cancer

Gene symbol Gene title Fold changea Adjusted
P-valueb
ANO1 anoctamin 1, calcium activated chloride channel 2.09 < 0.001
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.65 0.043
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 5.59 < 0.001
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.30 0.033
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 2.61 < 0.001
CLCA2 chloride channel accessory 2 0.46 0.017
CLIC4 chloride intracellular channel 4 0.75 0.008
CLIC6 chloride intracellular channel 6 5.86 < 0.001
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.20 0.020
GLRB glycine receptor, beta 3.42 < 0.001
KCNAB2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.72 0.013
KCND3 potassium voltage-gated channel, Shal-related subfamily, member 3 2.36 < 0.001
KCNE3 potassium voltage-gated channel, Isk-related family, member 3 0.75 0.003
KCNE4 potassium voltage-gated channel, Isk-related family, member 4 12.64 < 0.001
KCNJ3 potassium inwardly-rectifying channel, subfamily J, member 3 6.22 < 0.001
KCNK6 potassium channel, subfamily K, member 6 1.82 < 0.001
KCNMA1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 1.45 0.035
KCNN4 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 0.42 < 0.001
KCNS3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 1.58 0.028
MCOLN2 mucolipin 2 0.46 0.002
P2RX4 purinergic receptor P2X, ligand-gated ion channel, 4 1.82 < 0.001
SCN7A sodium channel, voltage-gated, type VII, alpha subunit 1.71 0.009
SCNN1A sodium channel, non-voltage-gated 1 alpha subunit 2.00 < 0.001
TPCN1 two pore segment channel 1 1.38 < 0.001
  1. aFold change is calculated by dividing the mean expression of ER positive tumor by the mean expression of ER negative tumor.
  2. bP-value is calculated by two-tailed t-test and adjusted by Benjamini & Hochberg correction.