Table 1 The RAD50 and MRE11 gene variants detected in laryngeal cancer (LC), multiple primary tumors with laryngeal cancer (MPT-LC), multiple primary tumors of head and neck (MPT) and controls
From: The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers
Gene | Exon/intron | Nucleotide change | Aminoacid change | LC n = 175 OR (95% CI) | MPT-LC n = 115 OR (95% CI) | MPT n = 68 OR (95% CI) | Controls n = 506 |
|---|---|---|---|---|---|---|---|
RAD50 | Ex. 4 | c.379G>A | p.V127I | 2 | - | - | 2 |
2.91 (0.41-20.85) | |||||||
Ex. 7 | c.943G>T | p.V315L | - | 2 | - | 1 | |
8.96 (0.81-99.68) | |||||||
Ex. 25 | c.3876C>T | - | 1 | - | - | 0/180 | |
8.71 (0.35-215) | |||||||
MRE11 | Int. 16 | c.1783-86delAG | - | 39 | 18 | 20 | 61/279 |
1.03 (0.65-1.62) | 0.66 (0.37-1.18) | 1.49 (0.82-2.69) |