Figure 6From: The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinomaDcR3 expression in human RCC specimens is PI3K/AKT-dependent. (A) Immunohistochemical analysis of DcR3 expression in ex vivo tissue samples 48 h after treatment with LY294002 (100 μM). Representative images are shown (magnification: 100×). (B) Immunoblot analysis of DcR3 and phospho-AKT protein levels in nine different pairs of RCC and respective normal renal tissue.Back to article page