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Table 2 Limiting dilution transplantation of mammary basal cells from control and K5ΔN βcat mice

From: Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis

Number of transplanted cells Control K5ΔN βcat
500 3/3 3/3
100 3/4 4/4
20 3/12 10/12
10 3/11 5/11
  1. Repopulating unit frequency in the basal cell population, as determined in limiting dilution transplantations: 1/66 (1/134-1/32) for control and 1/14 (1/23-1/8) for K5ΔNβcat; 95% CI, p value = 0.000284.