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Table 2 Limiting dilution transplantation of mammary basal cells from control and K5ΔN βcat mice

From: Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis

Number of transplanted cells

Control

K5ΔN βcat

500

3/3

3/3

100

3/4

4/4

20

3/12

10/12

10

3/11

5/11

  1. Repopulating unit frequency in the basal cell population, as determined in limiting dilution transplantations: 1/66 (1/134-1/32) for control and 1/14 (1/23-1/8) for K5ΔNβcat; 95% CI, p value = 0.000284.
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Molecular Cancer

ISSN: 1476-4598