Figure 5
From: Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines
Mesenchymal stem cells increase breast cancer cell symmetric self-renewing divisions and decreases frequency of asymmetric segregation of template DNA. (A) Cells were grown with MSCs after BrdU was removed, and examined for changes in asymmetric segregation of template DNA. Percentages of asymmetric segregation of template DNA are shown with standard error of the mean of triplicate co-culture experiments. (B) The percentage of breast cancer cells expressing the CD44+/CD4-/lo immunophenotype was quantified by flow cytometry before and after they were co-cultured with MSCs.