Table 1 Frequencies of BrdU asymmetric division, surface marker expression and functional assays in breast cancer cell lines
From: Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines
Cell line | % Asymmetric | % CD44+/ | HER2 | No. invaded | No. migrated | Soft agar |
|---|---|---|---|---|---|---|
| Â | cell division* | CD24-/lo | (MFI) | cells* | cells* | colony no.* |
Basal | Â | Â | Â | Â | Â | Â |
  MDAMB231 | 6.5 ± 0.6 | 99.9 | 9.4 | 83.5 ± 0.0 | 75.0 ± 5.9 | 45 ± 7 |
  HCC1143 | 6.3 ± 0.6 | 16.4 | 0 | 0.9 ± 0.3 | 4.9 ± 0.5 | 0 |
  MDAMB157 | 1.0 ± 0.3 | 97.4 | 73.5 | 32.0 ± 1.7 | 50.4 ± 2.6 | 0 |
  HBL100 | 0.6 ± 0.4 | 81.3 | 16.4 | 14.7 ± 1.5 | 9.3 ± 1.1 | 99 ± 16 |
  BT549 | 0.5 ± 0.3 | 90.3 | 0.4 | 14.1 ± 3.7 | 171.0 ± 8.2 | 0 |
  MDAMB468 | 0 | 1.6 | 2.9 | 3.2 ± 0.3 | 42.6 ± 1.4 | 390 ± 35 |
  HCC1954 | 0 | 2.5 | 851.9 | 20.4 ± 2.9 | 46.8 ± 2.5 | 1 ± 1 |
Luminal | Â | Â | Â | Â | Â | Â |
  MDAMB453 | ≤ 0.25 | 0 | 648.9 | 1.9 ± 0.2 | 5.9 ± 0.7 | 0 |
  SKBR3 | ≤ 0.25 | 0 | 1478.8 | 0.4 ± 0.1 | 3.7 ± 0.4 | 0 |
  MCF7 | 0 | 3.8 | 279.7 | 0.2 ± 0.1 | 2.8 ± 0.6 | 1 ± 0 |
  T47D | 0 | 0 | 89.7 | 0.6 ± 0.2 | 6.4 ± 0.3 | 13 ± 4 |
  MDAMB361 | 0 | 0.8 | 586.2 | 0.3 ± 0.1 | 3.3 ± 0.4 | 0 |