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Table 1 Correlation of PinX1 expression in tissue with patients’ clinicopathological variables in 187 cases of UCB

From: PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway

  

PinX1 expression (%)

Variables

All cases (N = 187)

Negative expression (N = 83)

Positive expression (N = 104)

P valuea

Age(years)

   

0.456

≤60b

80

33(41.3)

47(58.8)

 

>60

107

50(46.7)

57(53.3)

 

Gender

   

0.212

Male

166

71(42.8)

95(57.2)

 

Female

21

12(57.1)

9(42.9)

 

Tumor multiplicity

   

<0.001

Unifocal

79

17(21.5)

62(78.5)

 

Multifocal

108

66(61.1)

42(38.9)

 

WHO grade

   

0.844

G1

46

19(41.3)

27(58.7)

 

G2

66

29(43.9)

37(56.1)

 

G3

75

35(46.7)

40(53.3)

 

pT status

   

0.404

pT1

35

13(64.0)

22(36.0)

 

pT2

95

38(54.5)

57(45.5)

 

pT3

37

20(50.0)

17(50.0)

 

pT4

20

12(37.5)

8(62.5)

 

pN status

   

0.023

pN-

157

64(40.8)

93(59.2)

 

pN+

30

19(63.3)

11(36.7)

 

ki-67 index

   

0.004

≥50%

95

52(54.7)

43(45.3)

 

<50%

92

31(33.7)

61(66.3)

 
  1. aChi-square test. bmean age. UCB: urothelial carcinoma of bladder.