Figure 2
From: Tumor glycolysis as a target for cancer therapy: progress and prospects
Schematic showing the distribution of glycolytic enzymes in various subcellular compartments. HKII is a cytoplasmic enzyme however its localization to mitochondrial membrane has been established. As for binding with tubulin or actin filaments existing data are strong enough to include only GAPDH and for other glycolytic enzymes it remains to be known. The nuclear translocation has been well documented for the enzymes GAPDH, LDH, PFKFB3 and PK-M2.