Figure 2

Network of inflammatory response and corresponding transcripts. Networks were constructed with IPA software using genes DE involved in ‘inflammatory response’. A network is a graphical representation of the molecular relationships between molecules (nodes). The biological relationship between two nodes is represented as an edge (line) connecting two nodes. All edges are supported by information from the literature stored in the Ingenuity Pathways Knowledge Base. A solid line represents a direct interaction between two gene products and a dotted line means there is an indirect interaction. The intensity of the node color indicates the degree of up-regulation (red) or down-regulation (green) when comparing SiHa _CDV versus SiHa _parental cells. Canonical pathways identified by IPA in the networks are shown in blue while the functional annotations are shown in yellow.