CHD1L: a novel oncogene

Table 2 List of the studies of Chr1q and/or CHD1L amplification in cancer

Tumor origin	Chr1q/CHD1L	Technique used	Biological/clinical impact	References
Breast	Chr1q ( 67%)	CGH	genetic aberration	[6]
Bladder	Chr1q ( 54%)	CGH	Invasive cancer	[5]
	CHD1L	PCR	Poor prognosis	[31]
	Chr1q21-24	CGH + expression	Survival genes	[26]
Colorectal	CHD1L	FISH, PCR	Oncogene, Poor survival	[11]
Esophageal	Chr1q	CGH	Genetic aberration	[9]
Fibrosarcoma	CHD1L	CGH	Genetic defect	[10]
Liver	Chr1q21	CGH	Poor prognosis	[8]
	( 56 ~78%)	FISH	CHD1L was	[12]
	Chr1q21	TMA + IHC	Sequenced	[29]
	CHD1L		Poor prognosis
	CHD1L
Ovarian	CHD1L	TMA + IHC	Metastatic cancer with poor prognosis	[30]

ISSN: 1476-4598