Table 1 Results from univariate and multivariate survival analyses for a distant metastases-free survival of breast cancer patients

CRIP1

negative (0)

36

21 / 58%

positive (1+, 2+, 3+)

75

28 / 37%

p = 0.039

CRIP1 in lymph node-negative tumors

CRIP1 negative (0)

23

11 / 48%

CRIP1 positive (1+, 2+, 3+)

44

11 / 25%

p = 0.1 n.s.

CRIP1 in lymph node-positive tumors

CRIP1 negative (0)

13

10 / 77%

CRIP1 positive (1+, 2+, 3+)

33

17 / 52%

p = 0.09 n.s.

CRIP1 in HER2-negative tumors (0)

CRIP1 negative (0)

14

7 / 50%

CRIP1 positive (1+, 2+, 3+)

14

5 / 36%

p = 0.6 n.s.

CRIP1 in HER2-positive tumors (1+, 2+, 3+)

CRIP1 negative (0)

21

14 / 67%

CRIP1 positive (1+, 2+, 3+)

59

23 / 39%

p = 0.021

Multivariate Cox regression analysis

coefficient

chi²

p-value

nodal status

0.86

7.45

0.006

tumor size

0.51

4.58

0.03

CRIP1

−0.66

4.28

0.039 *

total p = 0.029