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Figure 2 | Molecular Cancer

Figure 2

From: MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells

Figure 2

MiR-32 and 3-UTR of PTEN. (A) Position of the miR-32 target site in 3-UTR of PTEN mRNA predicted by TargetScan. (B) Effect of miR-32 on PTEN expression by luciferase reporter assay. SW480 cells were cotransfected with miR-32 mimics(or miR-32 mimics-NC) with pmiR-PTEN-wt (or pmiR-PTEN-mut) vector. Luciferase activity was normalized by the ratio of firefly and Renilla luciferase signals. The results were expressed as fold change relative to the negative control.*P < 0.05 when compared to other three groups. Data were the means of three measurements and the bars represented SD of the mean.

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