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Table 1 Transcriptional changes induced by D6 treatment in melanoma cells and normal fibroblasts

From: Molecular changes induced by the curcumin analogue D6 in human melanoma cells

Cell type

Differentially expressed transcripts

Over-expressed

Under-expressed

 

(0.5 > FC > 2)

(FC > 2)

(FC < 0.5)

LB 24 DAGI Melanoma cells

1173 (6.2%)

681 (3.6%)

492 (2.6%)

BJ Fibroblasts

1883 (10%)

910 (4.8%)

973 (5.2%)

  1. Results from the statistical analysis conducted on microarrays gene expression data from LB24 melanoma cells and BJ fibroblasts, treated or not with 10 μM D6, are reported. Data shown represent the number / (percentages) of human transcripts that resulted differentially expressed (0.5 > FC > 2) by comparing treated and not treated samples. Detailed gene expression profile and statistical analysis procedures are described in the Methods section.
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Molecular Cancer

ISSN: 1476-4598