Regulation of protumorigenic pathways by Insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis

Table 2 GSEA summary of pathways associated with genes down regulated upon IGFBP2 knockdown

NAME	SIZE	NOM p-val	FDR q-val	FWER p-val
KEGG_CELL_CYCLE	49	0	0	0
KEGG_DNA_REPLICATION	28	0	0	0
KEGG_NUCLEOTIDE_EXCISION_REPAIR	15	0	0	0
KEGG_MISMATCH_REPAIR	15	0	0	0
KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION	15	0	2.19E-04	0.001
KEGG_HOMOLOGOUS_RECOMBINATION	15	0	1.83E-04	0.001
KEGG_PYRIMIDINE_METABOLISM	21	0	1.56E-04	0.001
KEGG_OXIDATIVE_PHOSPHORYLATION	19	0	0.00635	0.039
KEGG_PARKINSONS_DISEASE	21	0	0.01229	0.082
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	17	0.006186	0.013514	0.098
KEGG_SPLICEOSOME	32	0.002012	0.01617	0.128
KEGG_OOCYTE_MEIOSIS	30	0	0.02404	0.199
KEGG_P53_SIGNALING_PATHWAY	26	0	0.027815	0.247
KEGG_HUNTINGTONS_DISEASE	30	0.004098	0.032137	0.3
KEGG_WNT_SIGNALING_PATHWAY	21	0.045726	0.138961	0.804
KEGG_PURINE_METABOLISM	26	0.047431	0.150692	0.844
KEGG_GAP_JUNCTION	17	0.15251	0.155502	0.877
KEGG_TGF_BETA_SIGNALING_PATHWAY	15	0.393214	0.318836	0.995
KEGG_SMALL_CELL_LUNG_CANCER	15	0.55144	0.400925	0.999
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	25	0.517578	0.687552	1
KEGG_TIGHT_JUNCTION	16	0.787018	0.687305	1
KEGG_PATHWAYS_IN_CANCER	52	0.229814	0.731651	1
KEGG_ALZHEIMERS_DISEASE	38	0.433663	0.706543	1

ISSN: 1476-4598