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Table 7 Association of the combined risk genotypes of TNF-α SNPs with tumor HPV16-positive SCCOP patients

From: Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma

Risk groups1

HPV-positive cases

HPV-negative cases

Adjusted OR (95% CI)2

 

(n = 107)

(n = 69)

 

No.

%

No.

%

 

Low-risk group

18

16.8

32

46.4

1.0

Medium-risk group

25

23.4

16

23.2

2.7 (1.1-6.4)

High-risk group

64

59.8

21

30.4

5.4 (2.5-11.7)

  1. 1Low-risk group: individuals carrying 0–1 risk genotypes; medium-risk group: individuals carrying 2 risk genotypes; and high-risk group: individuals carrying 3 or 4 risk genotypes.
  2. 2Adjusted for age, sex, and smoking and alcohol drinking status.
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Molecular Cancer

ISSN: 1476-4598