Table 4 Predicted mRNA Targets of Up-Regulated miRNAs
Gene ID | Gene description | miRNAs | miRDB (target score) | TargetScan (Context + Percentile) |
|---|---|---|---|---|
TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase | miR-146a | 100 | 94,94,65,50,38,19 |
IRAK1 | Interleukin receptor associated kinase 1 | miR-146a | 87 | 98 |
BCORL1 | BCL6 corepressor-like 1 | miR-146a, miR-143, miR-548t | 77,68 | 98,80 |
NOVA-1 | Neuro-oncological ventral antigen1 | miR-146a, miR-143, miR-548l | 97,93,86 | 97,89,87 |
CCDC67 | Coiled-coil domain containing 67 | miR-22 | 77 | 99,97 |
Cbl | Cbl proto-oncogene, E3 ubiquitin protein ligase | miR-22, miR-222,miR-136, miR-3199,miR-1197 | 87,83,64,55 | 86,84,75,61,43,33,32,31 |
NET1 | Neuroepithelial cell transforming 1 | miR-22, miR-222,miR-143 | 93,61 | 98 |
ZFAND1 | Zinc finger, AN1-type domain 1 | miR-548h, miR-548l,has-miR-548t,miR-136 | 96,70 | 93,83,99,52 |
RGS6 | Regulator of G-protein signaling 6 | miR-222 | 75 | 91,96,12 |
CDKN1B | Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | miR-222 | 85 | 93,95 |
IGFBP5 | Insulin-like growth factor binding protein 5 | miR-143 | N/A | 99 |
RNASEL | Ribonuclease L | miR-146a, miR-548l | 74 | 81 |