Table 5 Predicted mRNA Targets of Down-Regulated miRNAs
GeneID | Gene Description | miRNAs | miRDB (target score) | TargetScan (Context + Percentile) |
|---|---|---|---|---|
ABHD3 | Abhydrolase domain containing 3 | miR-1244, miR-130a, miR-205 | 74, > 85 | 84 |
CCNJ | Cyclin J | miR-205-5p | 90 | 98 |
CHAMP1/ZNF828 | Chromosome alignment maintaining phosphoprotein 1 | miR-7-5p, miR-378a-3p | 60-96 | 96 |
MYB | v-Myb myeloblastosis viral oncogene homolog (avian) | miR-15b-5p, miR-16-5p | 74 | 96 |
PIK3CD | Phosphoinositide-3-kinase, catalytic, delta polypeptide | miR-7-5p | 94 | 91 |
VEGFA | Vascular endothelial growth factor A | miR-205, miR-15b | 79 | 97 |
FGD4 | RhoGEF and PH domain containing 4 | miR-17, miR-106a, miR-20a | 100 | 98 |
SPOPL | Speckle-type POZ protein-like | miR-9-3p | 97 | 97 |
RAB9B | RAB9B, member RAS oncogene family | miR-15b-5p, miR-16-5p, miR-130a-3P, miR-9-5p | 67-86 | 67-86 |
EGFR | Epidermal growth factor receptor | miR-7 | 81 | 93 |
E2F1 | E2F transcription factor 1 | miR-205, miR-17, miR-20b | 77 | 80 |
DOK4/IRS-5 | Docking protein 4 | miR-205 | N/A | 94 |