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Figure 4 | Molecular Cancer

Figure 4

From: Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway

Figure 4

Effects of MELK knockdown on the cytoskeleton and small Rho-GTPase activity. A, Images of NCI-N87/MELK-shRNA and control cells (100X). Scale bars = 200 μm. B, Immunostaining of phalloidin (F-actin) in NCI-N87/MELK-shRNA and control cells (100X). Red: F-actin; Blue: DAPI. Scale bars = 50 μm. C, Immunostaining of phalloidin (F-actin) and DAPI (nucleus) using confocal microscopy (400X). D, Small Rho-GTPase activity in NCI-N87/MELK-shRNA and control cells was measured by a Rhotekin-RBD or PAK-PBD pulldown assay. Data shows examples taken from one of three independent experiments.

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Molecular Cancer

ISSN: 1476-4598