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Table 2 Comparison of tumor development in nude mice

From: A mechanically-induced colon cancer cell population shows increased metastatic potential

Cell types

Number of animals

Mice (%) developing tumors

Mice (%) with more than one implantation site

Mean number of metastases in the liver

Mean mitotic rate

HCT8-E

7

71 (5/7)

40

3.4

7.6 ± 2.0

HCT8-R

16

69 (11/16)

73

5.1

7.3 ± 2.7

  1. HCT8-E and HCT8-R cells were injected into the spleen of nude mice as described in Methods. Spleen tumor implantation and liver metastases numbers were based on the evaluation of H&E stained slides following 9–10 weeks after injection.
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Molecular Cancer

ISSN: 1476-4598