Table 3 Measures of model performance of Nottingham Prognostic Index (NPI), without and without miR-10b RERs
From: Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients
A) Overall survival | |||||
|---|---|---|---|---|---|
Model | Calibration (p-value) | Survival C-index (95% CI) | Difference in C-index (p- value) | cNRI (95% CI) | cNRI (p-value) |
NPI | 0.999 | 0.849 (0.78-0.92) | 0.009 | 0.538 | 0.061 |
NPI+miR-10b RERs | 0.999 | 0.889 (0.82-0.96) | Events: 1/11 | ||
Nonevents: 30/70 | |||||
B) Disease free survival | |||||
NPI | 0.999 | 0.735 (0.656-0.815) | 0.050 | 0.496 | 0.015 |
Events: 1/25 | |||||
Nonevents: 30/56 | |||||
NPI+miR-10b RERs | 0.942 | 0.767 (0.676-0.859) | |||