Figure 6From: Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesisIL-23 signaling is upregulated in colon tumors of APC-Cldn1 mice. RNA was isolated from tumors of APCMin and APC-Cldn1 mice and was utilized for qRT-PCR analysis of the IL23 pathway associated genes (IL-23, IL-12p40, IL-17A and IL-6). Values are mean ± S.E.M. (n = 3 mice in each group).Back to article page