Table 2 Microarray analysis of APC-Cldn1 versus APC Min mice tumors
Signaling gene symbol | p-value | Fold change |
|---|---|---|
A. Wnt signaling related genes | ||
Tcf4 | 0.068 | 1.581 |
Lef1 | 0.017 | 2.238 |
Fzd10 | 0.016 | 2.219 |
Axin2 | 0.040 | 1.693 |
Wnt6 | 0.022 | 1.886 |
Wnt10a | 0.125 | 1.911 |
Sox17 | 0.064 | 2.694 |
Ephb6 | 0.029 | 2.527 |
B. Notch signaling related genes | ||
Tcf4 | 0.068 | 1.581 |
Lef1 | 0.017 | 2.238 |
Fzd10 | 0.016 | 2.220 |
Axin2 | 0.040 | 1.694 |
Mmp9 | 0.042 | 1.628 |
Atoh1 | 0.047 | -3.487 |
Klf4 | 0.010 | -2.495 |
Muc2 | 0.112 | -2.141 |
Muc3 | 0.002 | -6.700 |
Muc4 | 0.345 | -1.590 |
Tff3 | 0.184 | -1.789 |
C. lnflammation/lmmune response genes | ||
lL23a, p19 | 0.011 | 2.250 |
CxcI5 | 0.060 | 2.392 |
CxcI9 | 0.134 | 2.394 |
CxcI2 | 0.462 | 1.548 |
Mmp9 | 0.042 | 1.628 |
Nfat5 | 0.031 | 1.515 |
Pla2g5 | 0.002 | 2.796 |
Retn1b | 0.045 | 10.865 |
Lcn2 | 0.001 | 1.894 |
Ccl6 | 0.075 | 1.658 |
Ccl28 | 0.002 | 5.352 |
Ccl3 | 0.001 | 1.894 |
IL1b | 0.048 | 1.825 |
Csf3r | 0.056 | 1.567 |
Akt2 | 0.001 | 1.541 |
H2-AA | 0.017 | 1.764 |
H2-Eb1 | 0.051 | 1.666 |
CD244 | 0.010 | -2.207 |
Tff3 | 0.184 | -1.790 |
Muc2 | 0.112 | -2.141 |