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Figure 5 | Molecular Cancer

Figure 5

From: Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma

Figure 5

Inhibition of G9a induces autophagy and displays anti-tumor effects in a xenograft mouse model. (A) FaDu cells stably expressing luciferase-containing vectors with inducible-knockdown of G9a were orthotopically injected into mice. Tumors from eight mice fed with a control diet or nine mice fed with a diet containing doxycycline were quantified by measuring photon influx. A significant difference was determined between the groups (*, p < 0.05). (B) Tumors of mice were weighed after sacrifice. (C) Tumor lysates were subjected to western blot to analyze the indicated proteins.

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