The effect of Pfn1 expression on tumor growth of pancreatic cancer cell xenografts in vivo . (A) Representative micrographs of MIA PaCa-2-Ctrl (left) & MIA PaCa-2-Pfn1 (right) orthotopically injected nude mice. (B) Each tumor formed by the indicated cells was weighed. (C-D) Representative micrographs of SW1990-Ctrl & SW1990-shPfn1 subcutaneously injected nude mice. (E) Effect of Pfn1 knockdown (KD) on pancreatic cancer growth. (F) Each tumor formed by the indicated cells was weighed. Data are presented as mean ± SD from 5 mice in each group. *: P < 0.05.