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Figure 2 | Molecular Cancer

Figure 2

From: miR-27a regulates cisplatin resistance and metastasis by targeting RKIP in human lung adenocarcinoma cells

Figure 2

miR-27a promotes EMT and cisplatin resistance in vitro . A549 cells were transfected with NC or miR-27a mimics, A549/CDDP cells were transfected with anti-NC or miR-27a inhibitors respectively. Western blotting was used to detect E-cadherin and vimentin expression, β-actin was used as an internal control (A). transwell invasion assay (B) and MTT assay (C and D) were used to measure invasion ability and cisplatin sensitivity. Data are means of three separated experiments ± SD; *P < 0.01.

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