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Figure 4 | Molecular Cancer

Figure 4

From: Clinical relevance and therapeutic potential of angiopoietin-like protein 4 in hepatocellular carcinoma

Figure 4

ANGPTL4 suppressed in vivo invasiveness and metastasis of HCC. (A) Hematoxylin-eosin staining of liver and lung tissues between control and ANGPTL4 treatment group at week 6. The arrow heads in Ad-Luc group indicate the presence of tumor thrombus in the control group, while the arrowheads in the treatment group indicate the intact encapsulation surrounding the tumor. T, tumor; NT, non-tumor. (B) Ultrastructure of liver tumor tissues by transmission electron microscopy. In the control group, the liver tumor was observed to have (1) intact endothelial cells indicated by arrows, (2) infiltrated tumor cells into vessels and (3) invasive phenotype. In Ad-ANGPTL4 treatment group, the liver tumor was observed to have (4 & 5) disrupted endothelial cells indicated by the arrows and (6) intact tumor capsule.

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Molecular Cancer

ISSN: 1476-4598