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Table 1 Relationship between let-7d expression and clinicopathological features in RCC patients

From: Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7

 

Let-7d expression1(RQ: 2-ΔCt)

Variable

Case no.

Median

Range

P2

Gender

   

0.036

  Male

51

5.7 × 10-3

1.0 × 10-5-1.06

 

  Female

29

0.027

3.1 × 10-5-1.14

Age

   

0.19

<60(median)

35

7.4 × 10-3

2.1 × 10-5-0.655

 

  ≥60

45

8.5 × 10-3

1.0 × 10-5-1.14

T stage

   

<0.0001

  T1 and T2

50

0.046

1.9 × 10-4-1.14

 

  T3

30

9.2 × 10-4

1.0 × 10-5-0.067

G grade

   

<0.0001

  G1

27

0.28

2.8 × 10-3-1.14

 

  G2

38

5.8 × 10-3

2.1 × 10-5- 0.061

  G3

15

2 × 10-4

1.0 × 10-5-6.8 × 10-3

Histological type

   

0.069

  papillary RCC

2

0.026

  

  chromophobe RCC

3

2 × 10-4

 

  clear cell RCC

75

0.011

1 × 10-5-1.14

Vascular invasion

   

0.010

  positive

15

0.0014

1 × 10-5- 0.18

 

  negative

65

0.017

2.1 × 10-5-1.14

  1. 1Let-7d expression was normalized to U6.
  2. 2Mann–Whitney test for the comparison between two groups or Kruskal-Walis test for more groups.
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Molecular Cancer

ISSN: 1476-4598