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Table 2 Cell cycle analysis of REN cells

From: Agonist activation of estrogen receptor beta (ERβ) sensitizes malignant pleural mesothelioma cells to cisplatin cytotoxicity

Treatment/cell cycle phase

Go/G1

S

G2/M

Dead cells (sub G1)

Control

39 ± 1,9

33 ± 2,4

25 ± 0,5

3 ± 1

100 μM cisplatin (24 hrs)

39 ± 0,9

30 ± 2,3

23 ± 3,2

8 ± 2

10 nM KB9520 (2 hrs) + normal medium (24 hrs)

36 ± 1,9

29 ± 0,9

27 ± 0,9

8 ± 2

10 nM KB9520 (2 hrs) + 100 μM cisplatin (24 hrs)

48 ± 0,8

2 ± 2

28 ± 2,9

22 ± 1

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Molecular Cancer

ISSN: 1476-4598