Figure 7
From: ADAM17 mediates OSCC development in an orthotopic murine model
Tumors induced by injection of SCC-9 cells overexpressing ADAM17 (AD17-HA) have increased collagenase activity. C = tumors induced with SCC-9 overexpressing FLAG-GFP. ADAM17 = tumors induced with SCC-9 overexpressing ADAM17-HA. A: Collagenase activity is increased in SCC-9 overexpressing ADAM17-HA. B: Collagenase activity levels of ~100 kDa band in Figure A were calculated by band intensity using ImageJ software (n = 3, Student’s t-test p = 0.0285). C: shRNA-ADAM17 A431 cell conditioned media have reduced collagenase activity. D: Collagenase activity levels of ~100 kDa band in Figure C were calculated by band intensity using ImageJ software (n = 2, Student’s t-test p = 0.0370).