Table 2 OvMark results for known markers of ovarian cancer using the median cut-off
Gene symbol | Survival endpoint | Hazard ratio | P-value | Sample number |
|---|---|---|---|---|
LEPR [33] | OS/DFS | 1.14/1.08 | 0.04/0.28 | 1833/996 |
PRL [34] | OS/DFS | 1.05/1.25 | 0.49/6.78 × 10−3 | 1990/996 |
SPP1 [34] | OS/DFS | 1.13/1.17 | 0.05/0.03 | 1990/996 |
IGF2 [35] | OS/DFS | 1.22/0.99 | 0.06/0.99 | 709/422 |
SNAI2 [41] | OS/DFS | 1.28/1.30 | 5.89 × 10−5/3.37 × 10−4 | 1990/996 |
CXCL12 [42] | OS/DFS | 1.27/1.42 | 2.42 × 10−4/1.52 × 10−6 | 1833/996 |
ApoA1 [40] | OS/DFS | 1.02/1.17 | 0.77/0.03 | 1990/996 |
MIF [36] | OS/DFS | 0.89/0.89 | 0.09/0.13 | 1833/996 |
CA125 [37] | OS/DFS | 0.89/0.97 | 0.09/0.69 | 1651/924 |
BRCA1 [3] | OS/DFS | 1.13/1.01 | 0.04/0.26 | 1990/996 |
BRCA2 [3] | OS/DFS | 1.18/1.38 | 0.01/1.21 × 10−5 | 1833/996 |
CDKN1B [38] | OS/DFS | 1.18/1.14 | 9.13 × 10−3/0.07 | 1990/996 |
MLH1 [39] | OS/DFS | 0.98/0.81 | 0.78/5.18 × 10−3 | 1833/996 |
IFNG [43] | OS/DFS | 0.80/1.06 | 4.29 × 10−3/0.43 | 1833/996 |