Table 3 Clinico-pathological and genetic data for 22 GISTs
Tumor name | Sex | Age at diagnosis | Tumor location* | KIT WT status** | KIT Mutation | Stage at diagnosis*** | Fletcher **** | Histology ***** | Mitotic Index/50HPF | Complementary analysis |
|---|---|---|---|---|---|---|---|---|---|---|
1C2 | M | 53 | Sm | WT- | c.1653_1661del, p.552-554del | L | NA | F | >10 | CGH, FISH |
3C2 | M | 59 | Ga | WT- | c.1653_1670del, p.552_557del | M | HR | M | >10 | CGH |
4C | F | 42 | D | WT- | c.1708_1728del, p.570-576del | R | LR | F | 0 | CGH |
6C3 | M | 67 | R | WT- | c.1648-5_1670del, p.550-558del | R | HR | E | >10 | CGH |
18C3 | F | 47 | Sm | WT- | c.1679 T > A, p.V560D | R | NA | F | >10 | CGH |
20 s2 | M | 57 | Ga | WT- | c.1666_1680del, p.556_560del | M | HR | F | >10 | CGH, FISH |
28 s2 | F | 57 | D | WT- | c.1679_1681del, p.560del | R | NA | F | NA | NR |
29 s2 | M | 60 | Ga | WT- | c.1669_1674del, p.557_558del | R | HR | M | >10 | CGH |
30 s2 | M | 85 | M | WT- | c1669 T > A, pW557R | L | HR | F | >10 | NR |
31 s2 | M | 53 | Sm | WT- | c1658-1669del, p.553-556del | M | HR | F | >10 | NR |
32 s2 | F | 43 | Sm | WT- | c1670-1675Del, p.557_559delinsF | NA | NA | F | 2 | NR |
2P2 | M | 82 | Ga | WT+ | c.1670_1675del, p.557_559delinsF | M | HR | F | >10 | NR |
5C3 | F | 64 | D | WT+ | c.1669_1716del, p.557-572del | R | HR | M | NA | NR |
10C2 | M | 66 | Sm | WT+ | c.1669_1674del, p.557_558del | R | HR | F | >10 | NR |
14C2 | F | 60 | Ga | WT+ | c.1679_1681del, p.560del | R | HR | F | 2 | NR |
15C2 | F | 54 | Sm | WT+ | c.1676 T > G, p.V559G | R | IR | F | 1 | FISH |
22 s2 | F | 54 | Ga | WT+ | c.1679 T > G, p.V560G | NA | LR | F | 1 | NR |
23 s2 | F | 45 | Ga | WT+ | c.1658_1674delinsCTGAA, p.553-558delinsSE | NA | LR | F | 0 | NR |
24 s2 | F | 57 | D | WT+ | c.1673_1674insTCC, p.558delinsNP | R | LR | F | 0 | CGH |
12C2 | M | 39 | Ga | WT+ | c.1700_1726delinsGTTGTG, p.567-576SdelinSCV | R | HR | E | 0 | NR |
19 s2 | M | 55 | Ga | WT+ | c.1679 T > A, p.V560D | R | HR | E | >10 | CGH |
27 s2 | M | 59 | Ga | WT+ | c.1669_1680del, p.557-560del | R | HR | M | >10 | CGH |