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Table 3 Correlation of cytogenetic characteristics with CT antigen expression

From: The clinical value of the quantitative detection of four cancer-testis antigen genes in multiple myeloma

Characteristics

n

MAGE-C1

MAGE-A3

MAGE-C2

SSX

  

Level (Positive percentage)

Level (Positive percentage)

Level (Positive percentage)

Level (Positive percentage)

Del(13q14)

  

p < 0.01* (0.03*)

p = 0.03* (0.10)

p = 0.01* (0.20)

p = 0.25(0.15)

 

No

44

214.94 ± 830.59(72.7)

8.26 ± 27.53(65.9)

2.50 ± 8.54(70.5)

0.06 ± 0.22(15.9)

 

Yes

30

443.20 ± 838.11(93.3)

36.85 ± 127.23(83.3)

23.77 ± 98.61(83.3)

0.02 ± 0.06(30.0)

1q21

  

p = 0.13(0.68)

p = 0.11(0.10)

p = 0.02* (0.87)

p = 0.19(0.15)

 

No

44

207.45 ± 644.43(79.5)

6.89 ± 24.76(65.9)

0.60 ± 1.41(75.0)

0.04 ± 0.19(15.9)

 

Yes

30

454.18 ± 1050.80(83.3)

38.86 ± 127.58(83.3)

26.56 ± 98.45(76.7)

0.04 ± 0.14(30.0)

Del(17p13)

  

p = 0.85(0.59)

p = 0.69(1.00)

p = 0.38(1.00)

p = 0.19(0.33)

 

No

68

327.33 ± 868.73(79.4)

21.57 ± 87.60(72.1)

12.08 ± 66.07(75.0)

0.05 ± 0.18(23.5)

 

Yes

6

82.53 ± 118.21(100.0)

0.31 ± 0.53(83.3)

0.32 ± 0.74(83.3)

0.00 ± 0.00(0)

14q32

  

p = 0.79(0.94)

p = 0.67(0.05)

p = 0.68(0.42)

p = 0.74(0.86)

 

No

31

251.88 ± 645.46(80.60)

34.07 ± 125.46(61.30)

20.45 ± 95.93(71.00)

0.08 ± 0.26(22.60)

 

Yes

43

347.56 ± 954.95(81.40)

9.60 ± 28.30(81.40)

4.40 ± 17.23(79.10)

0.02 ± 0.07(20.90)

Del(13q14.3)

  

p = 0.04* (0.07)

p = 0.18(0.27)

p = 0.21(0.45)

p = 0.22(0.16)

 

No

48

233.06 ± 815.48(75.00)

7.71 ± 26.40(68.80)

2.62 ± 8.19(72.90)

0.05 ± 0.21(16.70)

 

Yes

26

444.86 ± 870.69(92.30)

42.25 ± 136.20(80.80)

26.83 ± 105.86(80.80)

0.02 ± 0.06(30.80)