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Figure 6 | Molecular Cancer

Figure 6

From: Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway

Figure 6

MiR-149 inhibits cell proliferation, invasion and migration of HCC cells in vitro by targeting AKT1/mTOR pathway. (A and B) Western blot analysis of AKT1, p-AKT1, mTOR and mTOR protein expression levels in HepG2 cells transfected with RNAi-AKT1 or RNAi-control vectors. (C-E) Overexpression of miR-149 fails to inhibit proliferation, invasion, and migration in AKT1 knockdown HepG2 cells.

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Molecular Cancer

ISSN: 1476-4598