Table 1 Gene set enrichment analysis of leukemia patient studies for our MLL-AF9 knockdown gene expression dataset
From: RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes
Patient study gene sets | Reference | FDR q-value | NES |
|---|---|---|---|
Top-100 gene set of MLL AML | Kohlmann et al. [1] | 0.008 | 1.48 |
Top-100 gene set of MLL leukemia irrespective of lineage | Kohlmann et al. [1] | 0.020 | 1.40 |
Top-100 probe set of pediatric MLL AML | Ross et al. [20] | 0.022 | 1.38 |
Downregulated in MLL AML | Rozovskaia et al. [21] | 0.005 | 1.69 |
Gene cluster 1 and 16 of 11q23 abnormal AML | Valk et al. [22] | 0.030 | 1.34 |
CML-BP versus CML-CP | Zheng et al. [23] | <0.001 | 1.96 |
Downregulated in CML-BP versus CML-CP | Zheng et al. [23] | <0.001 | 2.08 |