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Figure 5 | Molecular Cancer

Figure 5

From: Synthesis, identification and in vivo studies of tumor-targeting agent peptide doxorubicin (PDOX) to treat peritoneal carcinomatosis of gastric cancer with similar efficacy but reduced toxicity

Figure 5

Pulmonary metastases (panel A) and liver metastases (panel B) in this study. (A1)(B1) showed exact number of lung and liver metastases in each rabbit of the 4 groups, respectively; (A2 to A5) showed representative lung metastases in the Control, the HIPEC, the PDOX and the DOX, respectively; (B2 to B5) showed representative liver metastases in the Control, the HIPEC, the PDOX and the DOX, respectively; (A6) showed micrographs of lung metastases in the HIPEC, characterized by cancer invasion, pulmonary tissue suppression, intravascular tumor thrombus formation and conspicuous inflammatory cells infiltration (A6-1, HE stain, 200×)(A6-2, HE stain, 400×). (B6) showed micrographs of liver metastases in the Control, characterized by extensive liver tissue destruction, invading cancer cells, inflammatory cells infiltration, and hemorrhage in liver tissue (B6-1, HE stain, 100×)(B6-2, HE stain, 200×).

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Molecular Cancer

ISSN: 1476-4598