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Table 1 List of transcription factors differentially expressed between adjacent and healthy mucosa samples

From: Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer

Gene symbol Connections DEG connections Rank P-value Eccentricity Closenness centrality Healthy mucosa network
FOSB 4 4 1.000 <1.00E-04 9 0.209 NO
JUN 2 2 1.000 <1.00E-04 11 0.151 NO
NR4A2 5 5 1.000 <1.00E-04 9 0.204 NO
OSR2 12 12 1.000 <1.00E-04 8 0.234 NO
ZBTB16 1 1 1.000 <1.00E-04 9 0.200 NO
EGR2 10 9 0.900 <1.00E-04 8 0.247 NO
NR4A3 9 8 0.889 <1.00E-04 8 0.249 NO
EBF1 162 143 0.883 <1.00E-04 7 0.294 YES
HEY2 24 21 0.875 <1.00E-04 8 0.266 NO
NR4A1 16 14 0.875 <1.00E-04 8 0.240 NO
PRRX1 30 26 0.867 <1.00E-04 7 0.289 NO
EGR1 13 11 0.846 <1.00E-04 9 0.217 YES
FOS 6 5 0.833 <1.00E-04 10 0.178 NO
JUNB 5 4 0.800 <1.00E-04 10 0.178 NO
MEOX2 75 60 0.800 <1.00E-04 7 0.303 NO
ZFPM2 133 106 0.797 <1.00E-04 7 0.296 NO
ERG 76 60 0.789 <1.00E-04 8 0.287 NO
TSHZ2 109 85 0.780 <1.00E-04 7 0.302 NO
FOXC1 27 21 0.778 <1.00E-04 8 0.268 NO
HLF 84 65 0.774 <1.00E-04 7 0.301 NO
MEIS2 133 100 0.752 <1.00E-04 8 0.305 NO
CREB5 32 24 0.750 <1.00E-04 8 0.278 NO
PRDM6 83 62 0.747 <1.00E-04 7 0.293 NO
GLIS2 79 58 0.734 <1.00E-04 7 0.302 NO
HAND2 138 101 0.732 <1.00E-04 7 0.289 NO
EGR3 11 8 0.727 <1.00E-04 8 0.263 NO
SOX18 40 29 0.725 <1.00E-04 7 0.274 NO
ZNF423 79 57 0.722 <1.00E-04 8 0.303 YES
PHOX2B 60 42 0.700 <1.00E-04 8 0.275 YES
KLF7 133 92 0.692 <1.00E-04 7 0.313 NO
GLI3 217 150 0.691 <1.00E-04 7 0.325 NO
MEIS1 113 77 0.681 <1.00E-04 8 0.301 YES
KLF2 15 10 0.667 <1.00E-04 8 0.261 YES
TSHZ3 80 52 0.650 <1.00E-04 8 0.302 YES
NKX2-3 75 47 0.627 <1.00E-04 8 0.290 NO
BNC2 252 148 0.587 <1.00E-04 7 0.334 NO
PITX2 26 15 0.577 <1.00E-04 9 0.244 YES
PRDM8 70 40 0.571 <1.00E-04 7 0.304 YES
NR2F2 141 78 0.553 <1.00E-04 7 0.334 YES
TSC22D3 29 16 0.552 <1.00E-04 7 0.282 NO
PBX3 186 102 0.548 <1.00E-04 7 0.337 YES
ZEB1 264 139 0.527 <1.00E-04 7 0.343 YES
FOXF1 62 31 0.500 <1.00E-04 7 0.312 YES
ZNF532 110 52 0.473 <1.00E-04 7 0.326 YES
CAMTA1 68 30 0.441 <1.00E-04 7 0.318 YES
JAZF1 172 74 0.430 <1.00E-04 7 0.334 NO
AFF3 31 11 0.355 <1.00E-04 7 0.295 YES
NFIC 131 43 0.328 <1.00E-04 7 0.339 YES
ZEB2 74 24 0.324 <1.00E-04 7 0.324 YES
TCF4 408 129 0.316 <1.00E-04 6 0.371 YES
BCL6 36 11 0.306 <1.00E-04 7 0.309 NO
NR1H4 77 22 0.286 <1.00E-04 8 0.282 YES
MAFB 125 23 0.184 <1.00E-04 6 0.313 YES
HOXB13 93 14 0.151 <1.00E-04 8 0.264 NO
ATF3 4 3 0.750 0.0003 10 0.184 NO
ZBTB20 149 13 0.087 0.0183982 7 0.356 YES
THRB 12 2 0.167 0.0986901 8 0.259 YES
HOXB6 2 0 0.000 1 8 0.227 YES
IFI16 5 0 0.000 1 7 0.247 YES
NEUROD1 12 0 0.000 1 8 0.236 NO