Figure 7From: Chemoprevention of dietary digitoflavone on colitis-associated colon tumorigenesis through inducing Nrf2 signaling pathway and inhibition of inflammationA proposed pathway for digitoflavone-induced Nrf2/ARE-mediated cytoprotective proteins via activation of p38 MAPK signaling. Up-regulation of γ-GCSc, γ-GCSm explains the cytoprotective effects against oxidative stress in Caco-2 cells.Back to article page