Figure 2
From: Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer
CXCR4 and CXCR7 protein expression in human colon polyps, early and late stage carcinomas and metastases. Detection of CXCR4 protein expression assessed by immunohistochemical staining in representative specimens of polyp (B), primary stage I (C), II (D), III (E), IV (F) colon tumours, metastatic liver (H1&H2) and corresponding non-cancerous neighbour colon (A), and liver (G) tissues. Detection of CXCR7 protein expression in non-cancerous neighbour colon (I), primary stage IV colon tumor (J) and corresponding metastatic liver (K). Original magnification x200 (except H2, x400).