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Figure 3 | Molecular Cancer

Figure 3

From: miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer

Figure 3

Inhibition of miR-630 increased cell motility, migration, invasion and resistance to anoikis. Following transfection with miR-630 inhibitor or a negative control (NC) inhibitor in (i) HCC1954-Ag and (ii) SKBR3-Ag (A) motility, assessed by wound-healing assay (B) migration, through transwells; (C) invasion, through ECM-coated transwells; and (D) anoikis, on poly(hydroxyethyl methacrylic) acid coated plates; were found to be significantly changed as a consequence of miR-630 inhibition. Results represent n = 3 ± SEM, where * p <0.05, ** p <0.01.

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Molecular Cancer

ISSN: 1476-4598