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Figure 9 | Molecular Cancer

Figure 9

From: Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

Figure 9

Effect of porphyrins on protein RAS and ERK pathway . (A) Immunoblots showing the expression level of protein RAS in melanoma B78-H1 cells 24 h after treatment with porphyrins P2, P4 and C14 (1 and 5 μM) without irradiation. C14 at 5 μM reduces the level of protein RAS through a light-independent mechanism; (B) Immunoblots showing the levels of RAS, ERK, P-ERK, NF-κB and β-actin in untreated or porphyrin/light treated B78-H1 cells, 24 h after light treatment.

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Molecular Cancer

ISSN: 1476-4598