Figure 2
From: MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia
Effects of miR-155 transfection on the expression of selected putative target genes over 48 hours. Assessed by qRT-PCR at 6, 12, 24 and 48 hours after transfection of OCI-AML3 cells with Scrambled control (CTL, grey line) or miR-155 (black line). Results are depicted as mean fold change in mRNA expression + SEM relative to untreated control cells with baseline set to 1.0 (not shown). β-actin was used as the reference gene. Statistical significance was assessed using a Paired Two Tailed T-Test. *p < 0.05, **p < 0.01; n = 5-8.