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Figure 2 | Molecular Cancer

Figure 2

From: TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signaling

Figure 2

TFAP2B regulates cell proliferation. Human H1299 cells were transfected with two different sequences targeting TFAP2B (si-TFAP2B and si-TFAP2B-2) or an TFAP2B-overexpressing plasmid (p-TFAP2B). At 48 hours after transfection, the cell viability was determined by an MTT assay (A), and the cells were photographed (B). Cells treated with DMSO were used as the reference group, with the cell viability set at 100%. The percent cell viability in each treatment group was calculated relative to the cells treated with the vehicle control. The tumor cell H1299-induced colony formation was also analyzed (C), and the colony formation rate and colony size were calculated (D). The data are presented as the mean ± SD of three tests. *P < 0.05, significant differences between the treatment groups and control groups. si-NC means non-specific siRNA control.

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Molecular Cancer

ISSN: 1476-4598