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Figure 1 | Molecular Cancer

Figure 1

From: The negative interplay between Aurora A/B and BRCA1/2 controls cancer cell growth and tumorigenesis via distinct regulation of cell cycle progression, cytokinesis, and tetraploidy

Figure 1

Expression levels of Aur A/B and BRCA1/2. A-B, Protein expressions detected by Western Blotting showing the interactive regulation of Aur A/B and BRCA1/2 before and after treatment with various shRNAs in BRCA2 deficient pancreatic cancer cells Capan-1 (A) and in ovarian cancer cells OVCA433 (B). β-actin is used as a loading control. C-D, Relative mRNA levels of Aur A/B and BRCA1/2 in Capan-1 cells (C) and OVCA433 cells (D) detected by qRT-PCR compared with corresponding control cells (Scr cells). E-F, The protein levels of Aur A/B and BRCA1/2 in Capan-1 cells (E) and OVCA433 cells (F) treated with 20 μM MG132 for 3 h. β-actin is used as a loading control.

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Molecular Cancer

ISSN: 1476-4598