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Table 3 Performance of SCCA, POU3F3 and both SCCA and POU3F3 in the detection of different clinical stage ESCC

From: Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma

 

Clinical stage

P (Pearson Chi-square)

I

II

III

IV

Total

SCCA

26% (7/26)

35.9% (14/39)

76.4% (39/51)

87.1% (27/31)

59.2% (87/147)

0.000

POU3F3

69.2% (18/26)

66.6% (26/39)

78.4% (40/51)

74.2% (23/31)

72.8% (107/147)

0.455

SCCA + POU3F3

80.8% (21/26)

76.9% (30/39)

90.2% (46/51)

93.5% (29/31)

85.7% (126/147)

0.147

P (combination vs. SCCA)

0.000

0.001

0.109

0.671

0.000

 
  1. Abbreviations: SCCA squamous cell carcinoma antigen, statistic analysis, Pearson Chi-Square or Fisher’s Exact Test.